Published research on VIP (vasoactive intestinal peptide / aviptadil): record counts, recent publications, reviews and registered studies, pulled from PubMed and ClinicalTrials.gov. Part of other.
Ask TinaTina is an AI research guide who has read the published research collected here and shares it as objectively as she can, for free. She's not a doctor and doesn't give medical advice.
Registered studies by status: 0 recruiting, 1 active not recruiting, 4 completed.
Number of PubMed records mentioning VIP (vasoactive intestinal peptide / aviptadil), 2016 to 2026 (2026 is year to date).
Most recently started of 9 ClinicalTrials.gov entries.
Inhaled ZYESAMI (Aviptadil Acetate) for Treatment of Severe COVID-19NCT05137795 · Withdrawn · Phase 3 · started 2021-12-15Inhaled Aviptadil for the Treatment of COVID-19 in Patients at High Risk for ARDSNCT04536350 · Terminated · Phase 2 · started 2021-05-18Aviptadil for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial)NCT06729606 · Completed · Phase 3 · started 2021-04-20ACTIV-3b: Therapeutics for Severely Ill Inpatients With COVID-19NCT04843761 · Completed · Phase 3 · started 2021-04-20A Clinical Study Evaluating Inhaled Aviptadil on COVID-19NCT04844580 · Completed · Phase 2 · started 2021-03-10Inhaled ZYESAMI™ (Aviptadil Acetate) for the Treatment of Severe COVID-19NCT04360096 · Terminated · Phase 2 / Phase 3 · started 2021-02-15I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill PatientsNCT04488081 · Active Not Recruiting · Phase 2 · started 2020-07-31Intravenous Aviptadil for Critical COVID-19 With Respiratory FailureNCT04311697 · Completed · Phase 2 / Phase 3 · started 2020-05-15ZYESAMI (Aviptadil) Intermediate Population Expanded Access Protocol (SAMICARE)NCT04453839 · No Longer AvailablePrimary data for your own interpretation: published studies and regulator documents. No publisher opinion pieces.
Vasoactive Intestinal Peptide Induces Autophagy and Cytotoxicity in Renal Cell Carcinoma via SIRT3-Dependent Signaling Pathway.J Biochem Mol Toxicol · 2026 Apr · Li L et al. · PubMedAnticipated pharmacological role of Aviptadil on COVID-19.Environ Sci Pollut Res Int · 2021 Nov 30 · Mukherjee T et al. · PubMedPituitary adenylate cyclase-activating polypeptide/vasoactive intestinal peptide [Part 1]: biology, pharmacology, and new insights into their cellular basis of action/signaling which are providing new therapeutic targets.Curr Opin Endocrinol Diabetes Obes · 2021 Apr 1 · Moody TW et al. · PubMedAsk Tina for links to further coverageTina is an AI research guide who has read the published research collected here and shares it as objectively as she can, for free. She's not a doctor and doesn't give medical advice.
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