Published research on Thymosin alpha-1: record counts, recent publications, reviews and registered studies, pulled from PubMed and ClinicalTrials.gov. Part of other.
Ask TinaTina is an AI research guide who has read the published research collected here and shares it as objectively as she can, for free. She's not a doctor and doesn't give medical advice.
Registered studies by status: 11 recruiting, 2 active not recruiting, 24 completed.
Number of PubMed records mentioning Thymosin alpha-1, 2016 to 2026 (2026 is year to date).
Most recently started of 65 ClinicalTrials.gov entries.
AI-assisted Subtyping-directed Precision Treatment in Acute Aortic DissectionNCT07382375 · Not Yet Recruiting · NA · started 2027-12-31Thymalfasin for Immune Recovery in Adults With SepsisNCT07866118 · Recruiting · NA · started 2026-10-06Study of Adebrelimab Combined With Thymalfasin and Chemotherapy for Neoadjuvant Treatment of Esophageal CancerNCT07780721 · Not Yet Recruiting · Phase 2 · started 2026-08-30Thymosin-α1 for Recurrent Implantation FailureNCT07675980 · Recruiting · Phase 2 / Phase 3 · started 2026-02-11A Study Evaluating Neoadjuvant Chemotherapy, Concurrent Chemoradiotherapy Combined With Dual Immune Checkpoint Blockade in Patients With Locally Advanced Non-Small Cell Lung CancerNCT07103395 · Recruiting · Phase 2 · started 2026-01-01Phase II Trial of Neoadjuvant Thymalfasin, PD-1 Inhibitor, and Chemoradiotherapy for cStage III GEJ AdenocarcinomaNCT07277439 · Recruiting · Phase 2 · started 2025-12-16A Study Evaluating Concurrent Chemoradiotherapy Combined With Dual Immune Checkpoint Blockade for Limited-stage Small Cell Lung CancerNCT07103408 · Not Yet Recruiting · Phase 2 · started 2025-10-01Protective Effect of Ulinastatin and Thymosin α1 Against Negative Immune Dysregulation and Organ Dysfunction After Acute Aortic Dissection Surgery (PANDA XI)NCT06966687 · Enrolling By Invitation · NA · started 2025-04-01"Thymalfasin Immunotherapy Study with Triple Regimen in Advanced MSS/pMMR Colorectal Cancer"NCT06829355 · Recruiting · Phase 2 · started 2025-02-11Thymalfasin (Thymosin Alpha 1; Ta1) as an Enhancer of Vaccine Response Among Older Adults Receiving Booster Doses of COVID-19 VaccineNCT06821100 · Recruiting · Phase 1 · started 2024-12-02Neoadjuvant With Tα1 Plus Immuno-chemotherapy for Resectable NSCLCNCT06607926 · Unknown · NA · started 2024-10-15Thymalfasin and Recombinant Human IL-2 Injections in Treating Lymphocytopenia for Patients With Malignant Hematological TumorsNCT06584006 · Recruiting · Phase 2 · started 2024-09-01Primary data for your own interpretation: published studies and regulator documents. No publisher opinion pieces.
Preliminary results from a phase II trial of spatially fractionated radiotherapy combined with immunotherapy and anti-angiogenic therapy in patients with bulky solid tumors: early evidence of promising efficacy and favorable safety.Radiat Oncol · 2026 Apr 30 · Zhou Y et al. · PubMedThymalfasin combined with immune checkpoint inhibitors in the treatment of non-small cell lung cancer: A retrospective study on efficacy, safety, and immunological function.Pak J Med Sci · 2026 Mar · Wang P et al. · PubMedA Case Report of a Multisystemic Immune-Related Adverse Event Caused by Sintilimab in Combination With Thymosin Alpha-1.Clin Case Rep · 2026 Feb 8 · Li T et al. · PubMedThe efficacy and safety of thymosin alpha-1 combined with lenvatinib plus sintilimab in unresectable hepatocellular carcinoma: a retrospective study.Sci Rep · 2025 Apr 22 · Yao S et al. · PubMedComprehensive Review of the Safety and Efficacy of Thymosin Alpha 1 in Human Clinical Trials.Altern Ther Health Med · 2024 Jan · Dinetz E et al. · PubMedThe clinical efficacy and adverse effects of Entecavir plus Thymosin alpha-1 combination therapy versus Entecavir Monotherapy in HBV-related cirrhosis: a systematic review and meta-analysis.BMC Gastroenterol · 2020 Oct 19 · Peng D et al. · PubMedPharmacological development of the potential adjuvant therapeutic agents against coronavirus disease 2019.J Chin Med Assoc · 2020 Sep · Chen KH et al. · PubMedPharmacological and Genomic Approaches in Management of Cystic Fibrosis.Crit Rev Eukaryot Gene Expr · 2020 · Qadir MI et al. · PubMedSafety and Efficacy of Nucleic Acid Polymers in Monotherapy and Combined with Immunotherapy in Treatment-Naive Bangladeshi Patients with HBeAg+ Chronic Hepatitis B Infection.PLoS One · 2016 Jun 3 · Al-Mahtab M et al. · PubMedA multicenter, randomized, observation-controlled clinical trial to evaluate the efficacy and safety of thymalfasin adjuvant therapy in patients with HBV-related HCC after curative resection - first announcement of the protocol.Expert Opin Biol Ther · 2015 Jun 22 · Qiu SJ et al. · PubMedAsk Tina for links to further coverageTina is an AI research guide who has read the published research collected here and shares it as objectively as she can, for free. She's not a doctor and doesn't give medical advice.
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