Published research on CagriSema (cagrilintide + semaglutide): record counts, recent publications, reviews and registered studies, pulled from PubMed and ClinicalTrials.gov. Part of other.
Ask TinaTina is an AI research guide who has read the published research collected here and shares it as objectively as she can, for free. She's not a doctor and doesn't give medical advice.
Registered studies by status: 6 recruiting, 5 active not recruiting, 18 completed.
Number of PubMed records mentioning CagriSema (cagrilintide + semaglutide), 2016 to 2026 (2026 is year to date).
Most recently started of 31 ClinicalTrials.gov entries.
Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to CagrisemaNCT07817251 · Recruiting · Phase 3 · started 2026-09-16A Research Study to Compare Two Different Versions of Injectable CagriSema in People With Type 2 DiabetesNCT07357740 · Withdrawn · Phase 2 · started 2026-08-27A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 DiabetesNCT07282613 · Recruiting · Phase 3 · started 2026-08-04A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body WeightNCT07357766 · Withdrawn · Phase 3 · started 2026-06-22A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightNCT07564414 · Recruiting · Phase 3 · started 2026-05-21Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscle Health)NCT07527195 · Recruiting · Phase 1 · started 2026-04-10A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body WeightNCT07253285 · Recruiting · Phase 3 · started 2026-01-08A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to DietNCT07184086 · Active Not Recruiting · Phase 1 · started 2025-09-26The Role of the Amylin Analogue Cagrilintide in Bone MetabolismNCT07010432 · Recruiting · Phase 1 · started 2025-06-12A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-termNCT07011667 · Active Not Recruiting · Phase 3 · started 2025-06-03A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With ObesityNCT06780449 · Active Not Recruiting · Phase 3 · started 2025-02-10A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral NeuropathyNCT06797869 · Completed · Phase 2 · started 2025-01-29Positive coverage and opinions: this section collects news and commentary that read favorably.
Novo's CagriSema delivers superior weight loss versus tirzepatide in REIMAGINE 5 trialNovo Nordisk (via GlobeNewswire) · Sep 21, 2026Primary data for your own interpretation: published studies and regulator documents. No publisher opinion pieces.
Amylin and the renin-angiotensin system: risk or opportunity in amylin-based therapy?Lancet · 2025 Nov 6 · Muskiet MHA et al. · PubMedEfficacy and Safety of CagriSema for Metabolic Outcomes: Systematic Review and Pairwise Meta-Analysis of Randomized Controlled Trials.Diabetes Metab Syndr Obes · 2026 Sep 15 · Shao C et al. · PubMedCurrent and forthcoming pharmacotherapies for adolescent obesity: Evidence-based review.World J Clin Pediatr · 2026 Sep 9 · Fuentes-Mendoza JM et al. · PubMedPharmacological management of obesity: Current landscape and emerging therapies.Indian J Pharmacol · 2026 Sep 2 · Atal S et al. · PubMedEfficacy and Safety of Glucagon-like Peptide-1 Receptor Agonists and Co-agonists for Weight Loss Among Adults Without Diabetes : An Updated Systematic Review.Ann Intern Med · 2026 Sep 1 · Moiz A et al. · PubMedComparative efficacy and safety of glucagon-like peptide 1 based drugs for weight loss in adults with overweight or obesity without diabetes: network meta-analysis of randomised controlled trials.BMJ Med · 2026 Aug 27 · Chen D et al. · PubMedEfficacy and safety of once-weekly cagrilintide-semaglutide (CagriSema) in adults with type 2 diabetes inadequately controlled on diet and exercise (REIMAGINE 1): a randomised, double-blind, placebo-controlled, phase 3a study.Lancet Diabetes Endocrinol · 2026 Jun 7 · Aroda VR et al. · PubMedRenal or Hepatic Impairment Does Not Affect Pharmacokinetics, Safety, or Tolerability of Subcutaneous Cagrilintide.Clin Pharmacokinet · 2026 Jun 1 · Nielsen MJF et al. · PubMedCagrilintide and CagriSema for weight reduction and metabolic risk modification in overweight or obesity: a systematic review and meta-analysis.J Diabetes Metab Disord · 2026 May 20 · Rao H et al. · PubMedEfficacy and Safety of Cagrilintide and Cagrisema Versus Semaglutide as Anti-Obesity Medications: A Systematic Review, Meta-Analysis and Meta-Regression.Diabetes Obes Metab · 2026 Mar 16 · Ahmed M et al. · PubMedAsk Tina for links to further coverageTina is an AI research guide who has read the published research collected here and shares it as objectively as she can, for free. She's not a doctor and doesn't give medical advice.
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