Glutathione

Published research on Glutathione: record counts, recent publications, reviews and registered studies, pulled from PubMed and ClinicalTrials.gov. Part of other.

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Tina is an AI research guide who has read the published research collected here and shares it as objectively as she can, for free. She's not a doctor and doesn't give medical advice.

At a glance

33,706PubMed records

271Registered studies on ClinicalTrials.gov

263Randomized controlled trials

480Clinical trials

1,629Reviews

54Systematic reviews

Registered studies by status: 23 recruiting, 12 active not recruiting, 154 completed.

PubMed records by year

Number of PubMed records mentioning Glutathione, 2016 to 2026 (2026 is year to date).

1617181920212223242526

Latest publications

An "on-off-on" fluorescent probe based on nitrogen-doped carbon quantum dots for the selective detection of glutathione.Spectrochim Acta A Mol Biomol Spectrosc · 2026 Sep 7 · Duan H et al. · PubMed Dual-emissive polymeric nanoparticles-Ag nanoclusters hybrid for selective Ratiometric sensing of glutathione via Cu(II) displacement approach.Spectrochim Acta A Mol Biomol Spectrosc · 2026 Aug 27 · Tripathi A et al. · PubMed Facilely fabricating fluorescent iron-doped polymer dots nanozyme with oxidase-like activity for dual-mode analysis of glutathione S-transferase and its inhibitor.Spectrochim Acta A Mol Biomol Spectrosc · 2026 Aug 1 · Wang L et al. · PubMed Redox protection by bacterial glutathione peroxidase drives virulence in Pseudomonas aeruginosa.Redox Rep · 2026 May 22 · da Silva Cordeiro J et al. · PubMed Gut microbiota-regulated glutathione metabolic rhythms restore obesity-induced colonic inflammatory oscillations.Gut Microbes · 2026 May 9 · Zhao Z et al. · PubMed Sulfonated cobalt phthalocyanine coupled with poly(dopamine-co-sulfobetaine methacrylate) for single-cell electrochemical monitoring of glutathione.Biosens Bioelectron · 2026 Aug 29 · Qiu G et al. · PubMed Targeted LC-MS/MS profiling highlights altered cerebrospinal fluid glutathione in cancer patients with CNS metastases.J Pharm Biomed Anal · 2026 Jul 17 · Zhao X et al. · PubMed A coumarin-based water-soluble fluorescent probe for tandem detection of Cu(2+) and glutathione with application in bioimaging and real sample analysis.Spectrochim Acta A Mol Biomol Spectrosc · 2026 Jul 1 · Li B et al. · PubMed β-Amyloid and glutathione dysregulation cooperatively drive lipid peroxidation and ferroptosis in neuron-like cells.Free Radic Biol Med · 2026 Sep 16 · Radeen KR et al. · PubMed Synergistic transcriptional modules in Trichoderma asperellum enhance glutathione detoxification to counteract fungal pathogen toxins.Microbiol Res · 2026 Aug 22 · Han J et al. · PubMed Mitocurcumin disrupts glutathione balance by modulating Klf9/GSR axis to overcome platinum resistance in non-small cell lung cancer and restores immune surveillance in cold tumor.Free Radic Biol Med · 2026 Aug 17 · Panigrahi GC et al. · PubMed Statement of Retraction: Methyltransferase-like 3 silenced inhibited the ferroptosis development via regulating the glutathione peroxidase 4 levels in the intracerebral hemorrhage progression.Bioengineered · 2026 May 21 · PubMed

Reviews

Glutathione peroxidase in inflammatory bowel disease: From ferroptosis, immunity, and microbiota regulation to targeted nanomedicines.Life Sci · 2026 Sep 14 · Tang Y et al. · PubMed Glutathione in redox homeostasis: Bridging molecular mechanisms, bioavailability constraints, and translational challenges in systemic therapeutics.Biomed Pharmacother · 2026 Aug 12 · Carnib BL et al. · PubMed Extender-dependent effects of reduced glutathione on post-thaw boar sperm quality: A systematic review and meta-analysis.Anim Reprod Sci · 2026 Jul 3 · Pantecostoma RR et al. · PubMed Glutathione in brain oxidative stress: from redox chemistry to clinical imaging.Arch Toxicol · 2026 Sep 30 · Aoyama K · PubMed Postharvest senescence of green vegetables and the role of glutathione metabolism: current state of knowledge and future research opportunities.Front Plant Sci · 2026 Sep 9 · Bozzo GG et al. · PubMed A review of the potential benefits and limitations of oral glutathione supplementation.Inflammopharmacology · 2026 Jul 14 · Fathizadeh H et al. · PubMed Glutathione Biology in Neurodegenerative and Metabolic Diseases: Molecular Mechanisms, Pathophysiological Roles, and Therapeutic Perspectives.Int J Mol Sci · 2026 Aug 21 · Gromadzka G et al. · PubMed Ferroptosis-Based Nanotherapy for Pancreatic Ductal Adenocarcinoma Through Glutathione Depletion and Iron Accumulation.Int J Nanomedicine · 2026 Aug 18 · Yoon S et al. · PubMed

Clinical trial publications

Creatine plus β-Hydroxy-β-Methylbutyrate supplementation is associated with preserved glutathione redox-balance and redox-function associations in older adults: a secondary analysis of a randomized crossover trial.Biogerontology · 2026 Feb 19 · Ramos-Hernández R et al. · PubMed Sodium benzoate treatment linked to increased glutathione levels and improved positive and negative symptoms, global function, and quality of life in patients with clozapine-resistant schizophrenia: secondary analysis of a randomized clinical trial.Eur Neuropsychopharmacol · 2025 Dec 15 · Lin CH et al. · PubMed Changes in Glutathione Metabolites and Reactive Oxygen Species from Baseline to Post-Treatment in Breast Cancer Survivors with Psychoneurological Symptoms Receiving Acupuncture.Integr Cancer Ther · 2026 Feb 13 · Li H et al. · PubMed Amustaline/glutathione pathogen-reduced red cell hemoglobin utilization in complex cardiac surgery: A post hoc analysis of the phase 3 ReCePI trial.Transfusion · 2025 Nov 29 · Welsby IJ et al. · PubMed Transfusion of Amustaline/Glutathione Pathogen-reduced Red Blood Cells in Cardiac Surgery: A Randomized Phase 3 Clinical Trial.Anesthesiology · 2025 Aug 12 · Sekela ME et al. · PubMed Effectiveness of oral glutathione in reducing nitric oxide and IL-1α concentrations for clinical improvement in mild to moderate acne vulgaris: a randomized controlled trial.Acta Dermatovenerol Alp Pannonica Adriat · 2025 Sep · Mawu FO et al. · PubMed Human leukocyte antigen alloimmunization in a randomized trial of amustaline/glutathione pathogen-reduced red cells in complex cardiac surgery patients.Transfusion · 2025 Jan 13 · Norris PJ et al. · PubMed Therapeutic effects of reduced glutathione on liver function, fibrosis, and HBV DNA clearance in chronic hepatitis B patients.BMC Gastroenterol · 2025 Feb 7 · Wei Q et al. · PubMed

Registered studies

Most recently started of 271 ClinicalTrials.gov entries.

Balanced coverage

Primary data for your own interpretation: published studies and regulator documents. No publisher opinion pieces.

Enhanced in vitro cytotoxicity of G-rich ssDNA-templated Cu nanoclusters with multienzyme-like activity and glutathione depletion capacity.Spectrochim Acta A Mol Biomol Spectrosc · 2026 Jun 13 · Wei C et al. · PubMed Targeting glutathione peroxidase 4 in ferroptosis: from immune regulation to pharmacological development and translational applications.Front Pharmacol · 2026 Aug 27 · Yang Q et al. · PubMed Glutathione for skin lightening via intravenous, oral, and topical routes: a critical narrative review of current evidence, safety, and the evidence-practice gap.J Med Life · 2026 Jul · Aloraini K et al. · PubMed Efficacy and Safety of Glutathione Supplementation in Type 2 Diabetes & Diabetes Complications.Nutrients · 2026 Jul 1 · Au S et al. · PubMed Glutathione Supplementation in Parenteral Nutrition to Prevent Oxidative Stress Related Complications in Preterm Infants: A Narrative Review of Preclinical Efficacy and Safety Profile.Nutrients · 2026 Jun 26 · Lavoie JC et al. · PubMed Formulation-dependent differences in systemic glutathione availability: Comparative pharmacokinetics of orally dissolving film and tablet formulations in healthy adults.Eur J Pharm Biopharm · 2026 Jul 2 · Jung ES et al. · PubMed Efficacy and safety of injectable sodium hyaluronate with vitamin C, tranexamic acid, and glutathione for pigmented dark circles.J Dermatolog Treat · 2025 Oct 21 · Guo F et al. · PubMed Ask Tina for links to further coverage

Tina is an AI research guide who has read the published research collected here and shares it as objectively as she can, for free. She's not a doctor and doesn't give medical advice.

Search the sources yourself

PubMed: GlutathioneU.S. National Library of Medicine ClinicalTrials.gov: GlutathioneU.S. National Library of Medicine

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