Semax

Published research on Semax: record counts, recent publications, reviews and registered studies, pulled from PubMed and ClinicalTrials.gov. Part of cognitive and neurological research.

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Tina is an AI research guide who has read the published research collected here and shares it as objectively as she can, for free. She's not a doctor and doesn't give medical advice.

At a glance

208PubMed records

0Registered studies on ClinicalTrials.gov

1Randomized controlled trials

4Clinical trials

11Reviews

0Systematic reviews

Registered studies by status: 0 recruiting, 0 active not recruiting, 0 completed.

PubMed records by year

Number of PubMed records mentioning Semax, 2016 to 2026 (2026 is year to date).

1617181920212223242526

Latest publications

Multi-Layer Magnetic Shields Based on Fe-Based Nanocrystalline and Co-Based Amorphous Ribbons.Materials (Basel) · 2026 May 11 · Liang Y et al. · PubMed Digitally Guided Hybrid Maxillary Expansion with Supragingival Mandibular Miniplates for Class III Correction in Late Adolescents: A Pilot Clinical Study.J Clin Med · 2026 Apr 17 · Arcos I et al. · PubMed Therapeutic peptides in gerontology: mechanisms and applications for healthy aging.Front Aging · 2026 Apr 7 · Mavrych V et al. · PubMed Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.J Am Acad Orthop Surg Glob Res Rev · 2026 Jan 2 · Rahman OF et al. · PubMed [Effect of a combined physiotherapeutic approach on changes in functional parameters after endovitreal surgery of rhegmatogenous retinal detachment with a favorable anatomical outcome].Vestn Oftalmol · 2026 · Sheludchenko VM et al. · PubMed Modulation of neuropathological pathways by bioactive peptides and proteins/polypeptides: Targeting oxidative stress in neurodegenerative diseases.Neuropeptides · 2025 Sep 21 · Giri S et al. · PubMed Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice.Br J Pharmacol · 2025 Jul 21 · Liu R et al. · PubMed The Potential of the Peptide Drug Semax and Its Derivative for Correcting Pathological Impairments in the Animal Model of Alzheimer's Disease.Acta Naturae · 2025 Oct-Dec · Radchenko AI et al. · PubMed Effect of ACTH4-10Pro8-Gly9-Pro10 on anti-inflammatory cytokine (IL-4, IL-10, IL-13) expression in acute spinal cord injury models (male Sprague Dawley rats).F1000Res · 2025 Sep 22 · Asadullah A et al. · PubMed The Effect of Peptide Semax, an ACTH(4-10) Analogue, on Intracellular Calcium Dynamics in Rat Brain Neurons.Bull Exp Biol Med · 2025 Oct 31 · Kolbaev SN et al. · PubMed Genes That Associated with Action of ACTH-like Peptides with Neuroprotective Potential in Rat Brain Regions with Different Degrees of Ischemic Damage.Int J Mol Sci · 2025 Jun 28 · Filippenkov IB et al. · PubMed Robust Multifunctional Films with Excellent EMI Shielding, Anti-Peeling, and Joule Heating Performances Enabled by an Encapsulated Highly Conductive Fabric Strategy.Small · 2024 Nov 27 · Chen T et al. · PubMed

Reviews

Therapeutic peptides in gerontology: mechanisms and applications for healthy aging.Front Aging · 2026 Apr 7 · Mavrych V et al. · PubMed Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.J Am Acad Orthop Surg Glob Res Rev · 2026 Jan 2 · Rahman OF et al. · PubMed Modulation of neuropathological pathways by bioactive peptides and proteins/polypeptides: Targeting oxidative stress in neurodegenerative diseases.Neuropeptides · 2025 Sep 21 · Giri S et al. · PubMed [POSSIBLE ROLE OF TRANSTHYRETIN IN THE BIOLOGICAL MECHANISM OF THE REGULATORY PEPTIDE NEUROPROTECTION.].Mol Gen Mikrobiol Virusol · 2016 · Vyunova TV et al. · PubMed Sigmoidal maximal effect modeling of low-density lipoprotein cholesterol concentration and annual incidence of coronary heart disease events in secondary prevention trials.Pharmacotherapy · 2014 May · Charland SL et al. · PubMed [Neuroprotective effects of peptides bioregulators in people of various age].Adv Gerontol · 2013 · Umnov RS et al. · PubMed [Evolution of the stress concept].Vestn Ross Akad Med Nauk · 2008 · Sudakov KV · PubMed [Comparison of anticoagulant effects of regulatory proline-containing oligopeptides. Specificity of glyprolines, semax, and selank and potential of their practical application].Izv Akad Nauk Ser Biol · 2006 Mar-Apr · Liapina LA et al. · PubMed

Clinical trial publications

[The efficacy of semax in the tretament of patients at different stages of ischemic stroke].Zh Nevrol Psikhiatr Im S S Korsakova · 2018 · Gusev EI et al. · PubMed [The study of chronic partial denervation and quality of life in patients with motor neuron disease treated with semax].Zh Nevrol Psikhiatr Im S S Korsakova · 2007 · Serdiuk AV et al. · PubMed [Evaluation of therapeutic effect of new Russian drug semax in optic nerve disease].Vestn Oftalmol · 2000 Jan-Feb · Polunin GS et al. · PubMed [Effectiveness of semax in acute period of hemispheric ischemic stroke (a clinical and electrophysiological study)].Zh Nevrol Psikhiatr Im S S Korsakova · 1997 · Gusev EI et al. · PubMed

Balanced coverage

Primary data for your own interpretation: published studies and regulator documents. No publisher opinion pieces.

Quantitative MRI Pharmacokinetic Modeling and MALDI Mass Spectrometry Imaging Biodistribution of a pH Mapping MRI Contrast Agent.Theranostics · 2026 Jul 5 · Mohanta Z et al. · PubMed Synthetic Peptides in Pharmacy Compounding: Analysis of PCAC Recommendations and Industry Safety Standards.Int J Pharm Compd · 2026 Jul-Aug · Willis J et al. · PubMed Semax, a Copper Chelator Peptide, Decreases the Cu(II)-Catalyzed ROS Production and Cytotoxicity of aβ by Metal Ion Stripping and Redox Silencing.Bioinorg Chem Appl · 2025 Jun 3 · Tomasello MF et al. · PubMed The occurrence of putative cognitive enhancing research peptides in seized pharmaceutical preparations: An incentive for controlling agencies to prepare for future encounters of the kind.Drug Test Anal · 2020 Jan 29 · Vanhee C et al. · PubMed The Use of Human Induced Pluripotent Stem Cells for Testing Neuroprotective Activity of Pharmacological Compounds.Biochemistry (Mosc) · 2019 Nov · Novosadova EV et al. · PubMed Pharmacological Aspects of Neuro-Immune Interactions.Curr Pharm Des · 2018 · Tarasov VV et al. · PubMed [Neonatal injections of pharmacological agents and their remote genotype-dependent effects in mice and rats].Ontogenez · 2012 Nov-Dec · Poletaeva II et al. · PubMed Ask Tina for links to further coverage