Cerebrolysin

Published research on Cerebrolysin: record counts, recent publications, reviews and registered studies, pulled from PubMed and ClinicalTrials.gov. Part of cognitive and neurological research.

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Tina is an AI research guide who has read the published research collected here and shares it as objectively as she can, for free. She's not a doctor and doesn't give medical advice.

At a glance

637PubMed records

43Registered studies on ClinicalTrials.gov

61Randomized controlled trials

89Clinical trials

96Reviews

20Systematic reviews

Registered studies by status: 4 recruiting, 1 active not recruiting, 19 completed.

PubMed records by year

Number of PubMed records mentioning Cerebrolysin, 2016 to 2026 (2026 is year to date).

1617181920212223242526

Latest publications

Post-endovascular thrombectomy perfusion imaging (CT and MR) as a prognostic biomarker and patient-selection tool for adjuvant therapy: A systematic review, meta-analysis, and clinical threshold framework.J Stroke Cerebrovasc Dis · 2026 Aug 17 · Eichel R et al. · PubMed Very Early Short-Course Cerebrolysin After Tenecteplase and Mechanical Thrombectomy: A Case Report.Case Rep Neurol Med · 2026 Aug 28 · Ziąbska H et al. · PubMed Predictors of Psychoactive and Nootropic Substance Use Among Romanian University Healthcare Students: The Interplay Between Academic Anxiety and Educational Advancement.Healthcare (Basel) · 2026 Jul 11 · Caba IC et al. · PubMed Neuroprotective Effects of Cerebrolysin in Moderate Traumatic Brain Injury with Nonoperative Lesions: A 6-Month Prospective Cohort Analysis.Asian J Neurosurg · 2025 Nov 19 · Boontoterm P et al. · PubMed Retraction: Regional Comparison of the Neurogenic Effects of CNTF-Derived Peptides and Cerebrolysin in AβPP Transgenic Mice.J Alzheimers Dis · 2026 Apr 21 · PubMed Use of nootropics in Alzheimer's disease: An analysis of regulatory positions and drug policies in the countries of the Commonwealth of Independent States.Int J Risk Saf Med · 2025 Dec 30 · Alexandrova EG et al. · PubMed Retraction Note to: Timed Release of Cerebrolysin Using Drug-Loaded Titanate Nanospheres Reduces Brain Pathology and Improves Behavioral Functions in Parkinson's Disease.Mol Neurobiol · 2026 Apr 1 · Ozkizilcik A et al. · PubMed Retraction Note: Neurotrophic effects of Cerebrolysin in the Mecp2(308/Y) transgenic model of Rett syndrome.Acta Neuropathol · 2026 Mar 24 · Doppler E et al. · PubMed Editorial Expression of Concern: Neurofibrillary and neurodegenerative pathology in APP-transgenic mice injected with AAV2-mutant TAU: neuroprotective effects of Cerebrolysin.Acta Neuropathol · 2026 Mar 12 · Ubhi K et al. · PubMed Cerebrolysin-loaded platelet-rich plasma exosomes: Restoring immune homeostasis via TNF-α/IL-10 modulation and apoptosis targeting for spinal cord injury repair.J Spinal Cord Med · 2025 Jun 5 · Akbari-Gharalari N et al. · PubMed Cerebrolysin after Endovascular Thrombectomy in Stroke: 12‑Month Functional Outcomes in a Propensity‑Matched Cohort.Transl Stroke Res · 2026 Feb 25 · Staszewski J et al. · PubMed Cerebrolysin, hemorrhagic transformation, and anticoagulation timing after reperfusion therapy in stroke: post hoc secondary analysis of the CEREHETIS trial.Front Pharmacol · 2026 Jan 7 · Kalinin MN et al. · PubMed

Reviews

Clinical trial publications

Efficacy of Cerebrolysin Treatment as an Add-On Therapy to Mechanical Thrombectomy in Patients with Acute Ischemic Stroke Due to Large Vessel Occlusion in Anterior Circulation: Results of a 3-Month Follow-up of a Prospective, Open Label, Single-Center Study.Transl Stroke Res · 2025 May 6 · Staszewski J et al. · PubMed Speech Therapy Combined With Cerebrolysin in Enhancing Nonfluent Aphasia Recovery After Acute Ischemic Stroke: ESCAS Randomized Pilot Study.Stroke · 2025 Feb 17 · Homberg V et al. · PubMed [Cerebrolysin with reperfusion therapy in ischemic stroke: a prospective analysis of multimodal brain imaging data from the CEREHETIS trial].Zh Nevrol Psikhiatr Im S S Korsakova · 2025 · Kalinin MN et al. · PubMed [Cerebrolysin and the optimal timing of anticoagulation resumption in stroke: combined post hoc survival analysis of the CEREHETIS trial].Zh Nevrol Psikhiatr Im S S Korsakova · 2025 · Kalinin MN et al. · PubMed [Cerebrolysin in the preventive therapy of dementia in elderly patients with mild cognitive impairment: a three-year prospective comparative study].Zh Nevrol Psikhiatr Im S S Korsakova · 2024 · Ponomareva EV et al. · PubMed Add-on treatment with Cerebrolysin improves clinical symptoms in patients with ALS: results from a prospective, single-center, placebo-controlled, randomized, double-blind, phase II study.J Med Life · 2023 Dec · Firstenfeld AJ et al. · PubMed The effectiveness of cerebrolysin, a multi-modal neurotrophic factor, for treatment of post-covid-19 persistent olfactory, gustatory and trigeminal chemosensory dysfunctions: a randomized clinical trial.Expert Rev Clin Pharmacol · 2023 Dec 9 · Hamed SA et al. · PubMed Prospective Randomized Control Trial to Compare the Role of Injection Cerebrolysin for 10 Days Duration Against Placebo in Operated Cases of Degenerative Cervical Myelopathy.Spine (Phila Pa 1976) · 2022 Nov 15 · Sharma A et al. · PubMed

Registered studies

Most recently started of 43 ClinicalTrials.gov entries.

Combined Acupuncture-Based Therapy for Rehabilitation After Ischemic StrokeNCT07846488 · Not Yet Recruiting · NA · started 2026-12-01 Cerebrolysin After Reperfusion in Extended-window EndoVascular ThrombectomyNCT06339411 · Not Yet Recruiting · Phase 2 · started 2026-09-01 Safety and Feasibility of Using Cerebrolysin in the Treatment of Primary Intracerebral Hemorrhage - a Prospective Randomized Open Blinded End-point TrialNCT06899464 · Not Yet Recruiting · Phase 4 · started 2025-10-01 Cerebrolysin in Early Stroke Rehabilitation - Tertiary StudyNCT07043686 · Recruiting · NA · started 2025-06-13 Effects of Cerebrolysin on Language Ability in Non-fluent Aphasia Patients After Stroke: A Randomized, Placebo-controlled, Double-blinded, Single Center StudyNCT06897176 · Recruiting · Phase 4 · started 2025-03-12 Cerebrolysin as an Add-On Therapy to Standard Treatment of Basilar Artery OcclusionNCT06489925 · Unknown · EARLY_Phase 1 · started 2024-07 Cerebrolysin in Critically Ill Patients With DeliriumNCT06677502 · Enrolling By Invitation · NA · started 2024-01-01 CERebrolysin In CADASILNCT05755997 · Active Not Recruiting · Phase 2 · started 2023-11-29 A Prospective, Trial About Safety and Efficacy of Combined Treatment With Cerebrolysin in Acute Ischemic Hemispheric Stroke Patients Undergoing EndoVascular Treatment (EVT)NCT06070753 · Unknown · NA · started 2023-10-01 Combined Cerebrolysin and Amantadine Sulfate Administration for Patients With Traumatic Brain Injury in the ICUNCT06052787 · Completed · Phase 3 · started 2023-09-01 Efficacy of Prednisolone Versus Cerebrolysin in the Treatment of Bell's PalsyNCT05821075 · Recruiting · Phase 1 / Phase 2 · started 2023-08-24 Efficacy and Safety of Cerebrolysin on Prolonged Disorders of ConsciousnessNCT04427241 · Recruiting · Phase 4 · started 2023-06-01

Balanced coverage

Primary data for your own interpretation: published studies and regulator documents. No publisher opinion pieces.

An Adaptive, Time-Informed, Phenotype-Guided Pharmacological Framework for Severe Traumatic Brain Injury : A Hypothesis-Driven Narrative Review.J Korean Neurosurg Soc · 2026 Sep 1 · Choi JM et al. · PubMed Research-Evidence-Practice Gaps in Post-stroke Neuro-recovery Pharmacological Therapies in Asia.Cerebrovasc Dis Extra · 2026 Jul 29 · Chiu HC et al. · PubMed Retraction Note: Cerebrolysin Attenuates Exacerbation of Neuropathic Pain, Blood-Spinal Cord Barrier Breakdown and Cord Pathology Following Chronic Intoxication of Engineered Ag, Cu or Al (50-60 nm) Nanoparticles.Neurochem Res · 2026 May 16 · Sharma HS et al. · PubMed Biochemical and Pharmacological Studies on Kynurenic Acid Metabolism in the Helix pomatia-Snail Model of Learning and Memory.Biomolecules · 2026 Apr 18 · Baran H et al. · PubMed Efficacy and Safety of Cerebrolysin as an Adjunct to Mechanical Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis of Observational Studies.Brain Behav · 2026 Mar · Afridi A et al. · PubMed Cerebrolysin and Risk of Hemorrhagic Transformation: A Pooled Analysis of Recent Studies.J Clin Neurol · 2026 Mar · Alrabadi B et al. · PubMed Safety and feasibility of cerebrolysin in treatment of primary intracerebral hemorrhage (CLINCH)-a prospective, randomized, open-label, blinded endpoint pilot trial.Front Neurol · 2025 Oct 1 · Kobayashi A et al. · PubMed Safety and Efficacy of Cerebrolysin for Neurorecovery After Acute Ischemic Stroke: A Systematic Review and Meta-Analysis of 14 Randomized Controlled Trials.Cureus · 2025 Aug 26 · Patel PN et al. · PubMed Cerebrolysin as an Early Add-on to Reperfusion Therapy: Risk of Hemorrhagic Transformation after Ischemic Stroke (CEREHETIS), a prospective, randomized, multicenter pilot study.BMC Neurol · 2023 Mar 27 · Khasanova DR et al. · PubMed Effect of cerebrolysin on neurodevelopmental outcome of high risk preterm infants: A randomized controlled trial.J Neonatal Perinatal Med · 2022 · Samir A et al. · PubMed Ask Tina for links to further coverage