Oxytocin

Published research on Oxytocin: record counts, recent publications, reviews and registered studies, pulled from PubMed and ClinicalTrials.gov. Part of cognitive and neurological research.

Ask Tina

Tina is an AI research guide who has read the published research collected here and shares it as objectively as she can, for free. She's not a doctor and doesn't give medical advice.

At a glance

15,192PubMed records

931Registered studies on ClinicalTrials.gov

1,197Randomized controlled trials

1,414Clinical trials

1,439Reviews

181Systematic reviews

Registered studies by status: 79 recruiting, 8 active not recruiting, 555 completed.

PubMed records by year

Number of PubMed records mentioning Oxytocin, 2016 to 2026 (2026 is year to date).

1617181920212223242526

Latest publications

Salivary oxytocin and testosterone in empathic stress responding: a pilot study.Stress · 2026 Oct 9 · Heilmann K et al. · PubMed Carboxyl-enriched molecularly imprinted interface with enhanced electrostatic binding for ultrasensitive oxytocin detection in a portable electrochemical platform.Talanta · 2026 Sep 17 · Liu C et al. · PubMed Effect of domperidone and/or oxytocin on milk bromatological composition in bitches with hypogalactia after elective caesarean section.Theriogenology · 2026 Sep 28 · Menezes BDC et al. · PubMed Associations between human oxytocin receptor gene promoter DNA methylation and brain structural connectome in panic disorder in Korea.J Affect Disord · 2026 Aug 26 · Kim HJ et al. · PubMed Oxytocin preserves excitatory responsiveness of VTA dopaminergic neurons in PTSD model rats.IBRO Neurosci Rep · 2026 Sep 20 · Chen Q et al. · PubMed Perfusion response to treatment outcome: CEUS links oxytocin to HIFU efficacy prediction for uterine fibroids.Int J Hyperthermia · 2026 Sep 22 · Zhang DL et al. · PubMed Signaling mechanisms of vasopressin/oxytocin-type neuropeptide-induced muscle contraction in the sea cucumber Apostichopus japonicus.Comp Biochem Physiol C Toxicol Pharmacol · 2026 Sep 3 · Liu H et al. · PubMed Retraction statement: carbetocin versus oxytocin for prevention of postpartum hemorrhage in obese nulliparous women undergoing emergency cesarean delivery.J Matern Fetal Neonatal Med · 2026 May 12 · PubMed Nomogram for predicting HIFU efficacy in uterine fibroids: based on oxytocin-induced arterial-phase perfusion delay and ultrasound features.Int J Hyperthermia · 2026 Mar 1 · Zhang DL et al. · PubMed Early versus late combined amniotomy and oxytocin after mechanical cervical ripening-a secondary analysis of a randomized controlled trial.J Matern Fetal Neonatal Med · 2026 Jan 7 · Dakwar Shaheen J et al. · PubMed Nucleus accumbens oxytocin modulates avoidance-related behaviors following social isolation in prairie voles.Neuropharmacology · 2026 Jul 24 · Liu Y et al. · PubMed Association between oxytocin exposure in the second stage of labor and postpartum hemorrhage among nulliparous patients with neuraxial analgesia.Pregnancy (Hoboken) · 2026 Sep 29 · Bank RL et al. · PubMed

Reviews

Oxytocin as regulator of stress and inflammation in aging.Neurosci Biobehav Rev · 2026 Aug 25 · Wright KA et al. · PubMed Special Issue: "Oxytocin and the Regulation of Affect, Cognition and Behavior" Section: "Overarching Conceptualizations of Oxytocin and Its Biological Mechanisms".Neurosci Biobehav Rev · 2026 Oct 8 · Grinevich V · PubMed Vasopressin signaling and vasopressin-to-oxytocin receptor crosstalk in the regulation of parental caregiving behavior.Neurosci Res · 2026 Sep 3 · Inada K · PubMed Endometrial Preparation Strategies for Frozen Embryo Transfer in Women with Adenomyosis: A Systematic Review of Hormone Replacement Therapy, Gonadotropin-Releasing Hormone Agonist, and Oxytocin Antagonists.Int J Womens Health · 2026 Sep 21 · Christina NLL et al. · PubMed Role of Oxytocin in Obesity.Curr Diab Rep · 2026 Sep 21 · Williams AL et al. · PubMed Early Versus Delayed Oxytocin Augmentation in Nulliparous Women with Spontaneous Dysfunctional Labour: A Systematic Review and Meta-Analysis.Healthcare (Basel) · 2026 Sep 14 · Mappa I et al. · PubMed Intranasal oxytocin for alcohol use disorder: A systematic review and multilevel, bayesian, and variance meta-analyses of randomized clinical trial data.Psychoneuroendocrinology · 2026 Jun 11 · Santos VH et al. · PubMed Analgesic effect of oxytocin and its effectiveness in acute pain management: A systematic review.Semergen · 2026 Jun 10 · El Mouaddib H et al. · PubMed

Clinical trial publications

Early versus late combined amniotomy and oxytocin after mechanical cervical ripening-a secondary analysis of a randomized controlled trial.J Matern Fetal Neonatal Med · 2026 Jan 7 · Dakwar Shaheen J et al. · PubMed Association between salivary oxytocin concentration and social loneliness in older adults: Findings from an uncontrolled pre-post multimodal intervention study.Psychoneuroendocrinology · 2026 Jul 20 · Zaharia G et al. · PubMed Impact of oxytocin discontinuation on fetal heart rate and uterine contractility: A pre-specified ancillary analysis embedded within a randomized trial.Acta Obstet Gynecol Scand · 2026 Jul 17 · Lafforgue L et al. · PubMed Promoting self-compassion meditation with intranasal oxytocin in borderline personality disorder: a pilot study.Psychiatry Res · 2026 Jun 17 · Arqueros M et al. · PubMed A Quality-Improvement Study Evaluating Three Postpartum Prophylactic Oxytocin Rates and Blood Loss After Vaginal Birth.Obstet Gynecol · 2026 Jun 25 · Litman EA et al. · PubMed Oxytocin alone versus oxytocin plus papaverine for labor induction in primiparous women after catheter ripening: a randomized controlled trial.Am J Obstet Gynecol MFM · 2026 May 16 · Ganem N et al. · PubMed Effects of intranasal oxytocin on fear, pain and aversive memory.Neuropeptides · 2026 Apr 24 · Silva JU et al. · PubMed A pilot study on the role of the oxytocinergic system in gut microbiome composition in children with autism: baseline associations and effects of intranasal oxytocin.Brain Behav Immun · 2026 Apr 4 · Margaux E et al. · PubMed

Registered studies

Most recently started of 931 ClinicalTrials.gov entries.

3-hour Versus 12-hour Double-balloon Catheter for Labor InductionNCT07492186 · Not Yet Recruiting · NA · started 2027-03-01 AI-Based Oxytocin-Stimulated Smart Lactation Support VestNCT07765992 · Not Yet Recruiting · NA · started 2026-12-01 Effects of Maternal and Infant Massage on Breastfeeding and Mother-Infant BondingNCT07867054 · Not Yet Recruiting · NA · started 2026-11-01 Inducing Self-Dehumanization to Examine Oxytocin and Suicide RiskNCT06710964 · Not Yet Recruiting · NA · started 2026-10 Efficacy of Intravenous Oxytocin to Speed Recovery After THANCT07430228 · Enrolling By Invitation · Phase 2 · started 2026-10 Oromucosal Oxytocin and Vasopressin Modulation of Emotional Face AttentionNCT07838493 · Recruiting · NA · started 2026-09-18 Biological Profiles of Neuropeptides, Neurotrophins and miRNA in MigraineNCT07832032 · Not Yet Recruiting · started 2026-09-17 The Effects of Oxytocin on Fairness Perception and Related Prosocial BehaviorsNCT07815496 · Recruiting · NA · started 2026-09-05 Effects of Connective Tissue Massage in Patients With Chronic InsomniaNCT07770945 · Not Yet Recruiting · NA · started 2026-09 Effect of Oxytocin Bolus Versus Slow Infusion on Haemodynamic Stability During Caesarean Section Under Spinal AnaesthesiaNCT07784478 · Not Yet Recruiting · NA · started 2026-09-01 Effect of Intravenous Oxytocin on Post Dural Puncture Headache After Caesarean SectionsNCT07853924 · Not Yet Recruiting · Phase 4 · started 2026-09 Oxytocin in Postmenopausal WomenNCT07742124 · Recruiting · started 2026-08-20

Balanced coverage

Primary data for your own interpretation: published studies and regulator documents. No publisher opinion pieces.

Intranasal Oxytocin for Alcohol Use Disorder: A Randomized, Double-Blind, Placebo-Controlled Multisite Trial Assessing Efficacy and Safety.Alcohol Clin Exp Res (Hoboken) · 2026 Jul · Tiouririne NA et al. · PubMed Ask Tina for links to further coverage

Tina is an AI research guide who has read the published research collected here and shares it as objectively as she can, for free. She's not a doctor and doesn't give medical advice.

Search the sources yourself

PubMed: OxytocinU.S. National Library of Medicine ClinicalTrials.gov: OxytocinU.S. National Library of Medicine

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