Published research on Mazdutide: record counts, recent publications, reviews and registered studies, pulled from PubMed and ClinicalTrials.gov. Part of metabolic research.
Ask TinaTina is an AI research guide who has read the published research collected here and shares it as objectively as she can, for free. She's not a doctor and doesn't give medical advice.
Registered studies by status: 9 recruiting, 3 active not recruiting, 18 completed.
Number of PubMed records mentioning Mazdutide, 2016 to 2026 (2026 is year to date).
Most recently started of 43 ClinicalTrials.gov entries.
Efficacy of Mazdutide on Fatty PancreasNCT07803705 · Not Yet Recruiting · NA · started 2026-11-15Mazdutide Plus LNG-IUS for Fertility-Sparing Treatment of AEH or Early Endometrial CancerNCT07781150 · Not Yet Recruiting · Phase 2 · started 2026-11-01A Study of HRS-4729 Injection in Participants With Type 2 DiabetesNCT07843862 · Not Yet Recruiting · Phase 2 · started 2026-10Mazdutide for Remission of Type 2 Diabetes: Multicentre, Double Blind, Randomised, Placebo Controlled TrialNCT07767552 · Not Yet Recruiting · NA · started 2026-09-30Efficacy and Safety of Mazdutide in Patients With Type 2 Diabetes Mellitus and Moderate to Severe Nonalcoholic Fatty Liver Disease Previously Treated With SemaglutideNCT07713992 · Not Yet Recruiting · NA · started 2026-09-15Mazdutide for Weight Management and Gout in Adults With ObesityNCT07824895 · Not Yet Recruiting · Phase 4 · started 2026-09-15Pre-hepatectomy Rehabilitation in Obese MASLD-Complicated Living Liver Donors With Mazdutide (PRIME)NCT07718126 · Recruiting · Phase 4 · started 2026-09-01Body-weight Reduction Effect on Portal Hypertension in Compensated CirrhosisNCT07797101 · Not Yet Recruiting · NA · started 2026-09-01QUARTET-DKD: Quadruple Therapy for Type 2 Diabetic NephropathyNCT07775846 · Not Yet Recruiting · Phase 4 · started 2026-09-01Effect of Mazdutide on Coronary Plaque in Patients With Coronary Atherosclerosis and Overweight or ObesityNCT07657676 · Not Yet Recruiting · Phase 4 · started 2026-09-01Mazdutide for Adults With Prediabetes: A Randomized, Double-Blind, Placebo-Controlled Trial (DREAM-PRE)NCT07654062 · Not Yet Recruiting · Phase 4 · started 2026-07ASCEND-1: Lifestyle Intervention Plus Mazdutide for Weight ManagementNCT07517042 · Recruiting · NA · started 2026-06-10Positive coverage and opinions: this section collects news and commentary that read favorably.
Innovent Announces Mazdutide, First Dual GCG/GLP-1 Receptor Agonist, Received Approval from China's NMPA for Chronic Weight ManagementInnovent Biologics (via PR Newswire) · Jun 27, 2025Primary data for your own interpretation: published studies and regulator documents. No publisher opinion pieces.
Development and validation of a multiplexed LC-HRMS method for nine GLP-1 receptor agonists and its pharmaceutical application.J Chromatogr A · 2026 Jul 21 · Tong LH et al. · PubMedEfficacy and Safety of the Dual Glucagon-Like Peptide-1 and Glucagon Receptor Agonist Mazdutide in Predominantly Chinese Adults With Obesity and/or Type 2 Diabetes: A Systematic Review and Meta-Analysis.Diabetes Obes Metab · 2026 Jul 6 · Kamrul-Hasan ABM et al. · PubMedEfficacy and Safety of Dual GLP-1/Glucagon Receptor Agonism in Overweight and Obesity: A Class-Specific Systematic Review and Meta-Analysis.Diabetes Obes Metab · 2026 Sep 29 · Amjad MM et al. · PubMedComparative efficacy and safety of glucagon-like peptide 1 based drugs for weight loss in adults with overweight or obesity without diabetes: network meta-analysis of randomised controlled trials.BMJ Med · 2026 Aug 27 · Chen D et al. · PubMedEfficacy and safety of mazdutide in adults with obesity or overweight: a US-based, multicentre, phase 2, randomised, placebo-controlled clinical trial.Lancet Diabetes Endocrinol · 2026 Aug 21 · Hsia SH et al. · PubMedObesity pharmacotherapy reimagined: The era of multi-receptor agonists and next-generation metabolic modulators, perspectives and controversies.Metabol Open · 2026 Mar 23 · Lempesis IG et al. · PubMedEfficacy and Safety of Mazdutide in Managing Overweight and Obesity Among Non-Diabetic Adults: A Meta-Analysis of Randomised Controlled Trials.Diabetes Obes Metab · 2026 Mar 10 · Azam MH et al. · PubMedComparative Efficacy and Safety of Glucagon Receptor Agonists on Metabolic Outcomes: A Network Meta-Analysis of Randomised Controlled Trials.Endocrinol Diabetes Metab · 2026 Mar · Abulehia A et al. · PubMedEmerging pharmacotherapies for obesity: A systematic review.Pharmacol Rev · 2024 Nov 22 · Kokkorakis M et al. · PubMedEfficacy and Safety of Mazdutide in Chinese Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial.Diabetes Care · 2024 Jan 1 · Zhang B et al. · PubMedAsk Tina for links to further coverageTina is an AI research guide who has read the published research collected here and shares it as objectively as she can, for free. She's not a doctor and doesn't give medical advice.
Third-party links, listed for reference. Educational information only, not medical advice. Hypnotic Dose does not endorse any product.